Protein Info for JDDGAC_14080 in Escherichia coli ECRC98

Name: yacH
Annotation: Uncharacterized protein YacH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF11737: DUF3300" amino acids 74 to 333 (260 residues), 266.4 bits, see alignment E=1e-83

Best Hits

Swiss-Prot: 97% identical to YACH_ECOLI: Uncharacterized protein YacH (yacH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecs:ECs0121)

Predicted SEED Role

"FIG01200701: possible membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>JDDGAC_14080 Uncharacterized protein YacH (Escherichia coli ECRC98)
MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVETQSTQLAVSDAAAVTLPATVS
APPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTYPTNVAQAVQWSHDNPLKQ
GDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNLGDAFLAQPQDVMDSVQRLRQ
LAQQTGSLKSSTEQKVITTTKKTVPVTQTVTAPVIPSNTVSTANPVITEPATTVISIEPG
NPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEPFVDSFVRGFGYSMGVATTYALFSS
IDWDDDDHDHHHHDDDNYHHHDGGHRDGNGWQHNGDNINIDVNNFNRITGEHLTDKNMAW
RHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSATQLPAPTRDSQRQAAASQFQQRTHAAPV
ITRDTQRQAAAQRFNEAEHYGSYDDFRDFSRRQPLTQQQKDAARQRYQSASPEQRQAVHE
KMQTNPQNQQRREAARERIQPASPEQRQAVREKMQTNPQIQQRRDAARERIQSASPEQRQ
VFKEKVQQRPLNQQQRDNARQRVQSASPEQRQVFREKVQESRPQRLNDSNHTARLNNEQR
SAVRERLSERGARRLER