Protein Info for JDDGAC_13510 in Escherichia coli ECRC98

Name: tssA
Annotation: Type VI secretion system protein TssA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 TIGR03362: type VI secretion-associated protein, VC_A0119 family" amino acids 11 to 466 (456 residues), 506.9 bits, see alignment E=3.4e-156 PF06812: ImpA_N" amino acids 26 to 112 (87 residues), 30.7 bits, see alignment E=3e-11 PF16989: T6SS_VasJ" amino acids 223 to 465 (243 residues), 237.9 bits, see alignment E=1.3e-74

Best Hits

KEGG orthology group: K11910, type VI secretion system protein VasJ (inferred from 100% identity to etw:ECSP_0224)

Predicted SEED Role

"Uncharacterized protein ImpA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>JDDGAC_13510 Type VI secretion system protein TssA (Escherichia coli ECRC98)
MAMDLRDPNVWISHLLENLPEEKLASALKDDNPDWEYIDGEIVKLGSLAHAQLDIPELQR
RGLQLLASESKDFRLLAHLLRTLQHAGDPLLALHLLTLYVEHYWTVAAPQNMAHKKRFAS
QIIKRFETGIEGFSQNAATTQRDTLLGELAKLAQCWQSHNVPELAQATDDLFALYQRTFN
RAAPAPVPTPAASGSSPQTTVTSESGVTQPSAPAPQIAIDSHDDKAWRDTLLKVAAILCE
RQPDSPQGYRLRRHALWQSITSTPQAESDGRTPLAAVSADMVADYQSRLASADMALWQQV
EKSVLLAPYWLDGHCLSAQTALRLGYKQVADTIRDEVIRFLERLPQLTGLLFNDRTPFLS
EQTKQWLAASPDGKVAPVAQIGEESQAARACFAGQGLEAALRYLDMLPEGDPRDQFHRQY
LAAQLTEEAGLIQLAQQQYRMLLMIGSQMMVSDWEPSLLTQLEQKFTAEQ