Protein Info for JDDGAC_13480 in Escherichia coli ECRC98

Name: fha
Annotation: Type VI secretion system protein Fha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 TIGR03354: type VI secretion system FHA domain protein" amino acids 9 to 418 (410 residues), 339.4 bits, see alignment E=3e-105 PF00498: FHA" amino acids 35 to 100 (66 residues), 21.3 bits, see alignment E=2.9e-08 PF20232: T6SS_FHA_C" amino acids 242 to 415 (174 residues), 142.8 bits, see alignment E=1.1e-45

Best Hits

KEGG orthology group: K11894, type VI secretion system protein ImpI (inferred from 100% identity to ece:Z0258)

Predicted SEED Role

"Uncharacterized protein ImpI/VasC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>JDDGAC_13480 Type VI secretion system protein Fha (Escherichia coli ECRC98)
MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHAPECHWSVQDRQQSIPAQAFTVI
LHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRLMVRVHLNRGDIPHYDEEM
ATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVVNGFSADPLQALQSESLITTG
DPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASPGDHNDDISAAEMAQRHLAVTPL
LRGLGGSLTVSNSDDADDFLEEAGRTLQAAIKGLLDLQQQRNSLSDKHLRPLEDNPLRLN
MDYATALDVMFAEGKSPVHLAAPAAVSESLRNVRHHEEANRAAIVESLRVLLDAFSPQNL
LRRFVQYRRSHELRQPLDDAGAWQMYSHYYEELASDRQQGFEMLFNEVYAQVYDRVLREK
QREPEA