Protein Info for JDDGAC_07610 in Escherichia coli ECRC98

Name: cah
Annotation: calcium-binding autotransporter Cah

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 949 signal peptide" amino acids 1 to 53 (53 residues), see Phobius details PF13018: ESPR" amino acids 6 to 52 (47 residues), 49.6 bits, see alignment 8.6e-17 TIGR04415: autotransporter passenger strand-loop-strand repeat" amino acids 110 to 142 (33 residues), 24.1 bits, see alignment (E = 1.4e-09) amino acids 164 to 192 (29 residues), 27 bits, see alignment (E = 1.8e-10) amino acids 211 to 245 (35 residues), 23.4 bits, see alignment (E = 2.3e-09) amino acids 248 to 283 (36 residues), 30.7 bits, see alignment (E = 1.2e-11) amino acids 339 to 375 (37 residues), 35 bits, see alignment (E = 5.4e-13) amino acids 357 to 394 (38 residues), 26.3 bits, see alignment (E = 3e-10) PF16168: AIDA" amino acids 143 to 192 (50 residues), 33.2 bits, see alignment 9.1e-12 amino acids 258 to 313 (56 residues), 31.4 bits, see alignment 3.2e-11 amino acids 325 to 386 (62 residues), 70.9 bits, see alignment 1.5e-23 amino acids 397 to 456 (60 residues), 46.5 bits, see alignment 6.3e-16 PF18883: AC_1" amino acids 480 to 600 (121 residues), 66.7 bits, see alignment E=3.7e-22 PF03797: Autotransporter" amino acids 660 to 925 (266 residues), 76.6 bits, see alignment E=5.7e-25

Best Hits

KEGG orthology group: K12687, antigen 43 (inferred from 100% identity to eoj:ECO26_1353)

Predicted SEED Role

"Antigen 43 precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (949 amino acids)

>JDDGAC_07610 calcium-binding autotransporter Cah (Escherichia coli ECRC98)
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAG
ETVNDGTLTNHDNQIVFGTANGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGR
QVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVHEGGVATGTIINRDGYQSVKS
GGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHA
GGEATAVTQNTGGALVTSTAATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQN
TLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTNASGKFSIDGTSGQASGLLLE
NGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVIN
GGQATGKTWLAFTNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTL
NRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQG
GHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGS
LETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDM
TFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSR
NGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF