Protein Info for JDDGAC_05600 in Escherichia coli ECRC98

Name: rrrD
Annotation: endolysin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details PF00959: Phage_lysozyme" amino acids 48 to 153 (106 residues), 74.9 bits, see alignment E=3.5e-25

Best Hits

KEGG orthology group: K01185, lysozyme [EC: 3.2.1.17] (inferred from 100% identity to ecs:ECs4962)

Predicted SEED Role

"Probable lysozyme from lambdoid prophage DLP12 (EC 3.2.1.17)" (EC 3.2.1.17)

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.17

Use Curated BLAST to search for 3.2.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (166 amino acids)

>JDDGAC_05600 endolysin (Escherichia coli ECRC98)
MPKLPAPLRKKLIALVLAGAGTFTIATHYTGYWEGKENSTYIDPTGTPTICYGHTGPDVK
PGMTLTDEECLELLEKDMKWAFAAIDRRVQVPLTRGQTVALASWIFWAGETNFRNSTLLR
LINAGQMPASCKQYIRWIYSKGVKLPGLEARRSADEWLCRYDLPKV