Protein Info for JDDGAC_01700 in Escherichia coli ECRC98

Name: selO
Annotation: protein adenylyltransferase SelO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 PF02696: SelO" amino acids 2 to 450 (449 residues), 507.5 bits, see alignment E=1.8e-156

Best Hits

Swiss-Prot: 100% identical to SELO_ECO5E: Protein adenylyltransferase SelO (selO) from Escherichia coli O157:H7 (strain EC4115 / EHEC)

KEGG orthology group: K08997, hypothetical protein (inferred from 100% identity to eok:G2583_2103)

MetaCyc: 98% identical to protein adenylyltransferase SelO (Escherichia coli K-12 substr. MG1655)
RXN0-7371 [EC: 2.7.7.108]

Predicted SEED Role

"Selenoprotein O and cysteine-containing homologs"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.108

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (478 amino acids)

>JDDGAC_01700 protein adenylyltransferase SelO (Escherichia coli ECRC98)
MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGETL
LPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDG
RAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVEPGAMLMRVAPSHLRFGH
FEHFYYRREPDKVRQLADFAIRHYWSHLEDDEDKYRLWFNDVVARTASLIAQWQTVGFAH
GVMNTDNMSLLGLTLDYGPFGFLNDYEPGFICNHSDHQGRYSFDNQPAVALWILQRLAQT
LSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDY
TRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPA
LVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS