Protein Info for JDDGAC_00275 in Escherichia coli ECRC98

Name: fliK
Annotation: flagellar hook length control protein FliK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF02120: Flg_hook" amino acids 250 to 328 (79 residues), 74.3 bits, see alignment E=2.8e-25

Best Hits

Swiss-Prot: 98% identical to FLIK_ECOLI: Flagellar hook-length control protein (fliK) from Escherichia coli (strain K12)

KEGG orthology group: K02414, flagellar hook-length control protein FliK (inferred from 100% identity to ece:Z3033)

Predicted SEED Role

"Flagellar hook-length control protein FliK" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>JDDGAC_00275 flagellar hook length control protein FliK (Escherichia coli ECRC98)
MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK
GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA
DDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP
GTPAQPLTPQVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW
QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSSHQHVRAALEAA
LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTVNHEPLAGEDDDTLPVPVS
LQGRVTGNSGVDIFA