Protein Info for IAI46_25050 in Serratia liquefaciens MT49

Annotation: ribose operon transcriptional repressor RbsR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF00356: LacI" amino acids 3 to 48 (46 residues), 75.2 bits, see alignment 5.7e-25 PF00532: Peripla_BP_1" amino acids 60 to 317 (258 residues), 117.1 bits, see alignment E=2.1e-37 PF13407: Peripla_BP_4" amino acids 62 to 309 (248 residues), 65.5 bits, see alignment E=1.2e-21 PF13377: Peripla_BP_3" amino acids 169 to 330 (162 residues), 145.7 bits, see alignment E=2.9e-46

Best Hits

Swiss-Prot: 71% identical to RBSR_ECOLI: Ribose operon repressor (rbsR) from Escherichia coli (strain K12)

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 97% identity to spe:Spro_4896)

MetaCyc: 46% identical to DNA-binding transcriptional repressor PurR (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Ribose operon repressor" in subsystem D-ribose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (333 amino acids)

>IAI46_25050 ribose operon transcriptional repressor RbsR (Serratia liquefaciens MT49)
MATMKDVARLAGVSTSTVSHVINNNRFVSDSVRAKIMAAIEQLNYAPSALARSLKLNQTR
TIGMLVTSSNNPFYAEVVRGVERSCYERGYSLILCNTEEDAARMNRNMETLLQKRVDGLL
LMCTENHRPSQDALSRYPSLPIVMMDWAPFEGANDIIQDNSLLGGEMATDHLIARGYRKI
ACIAGPQDKTTARHRLEGYRSAMQRAGLAILPGYEVHCDFEFEGGVIAMKQLLALAEPPH
AVFAGNDAVAVGAYQALYQAGLSVPQDMAVMGYDDIELAKYLAPPLSTIHQPKDSLGELA
IDALINRLQNPEREAQVLVLTPELVERASVGRR