Protein Info for IAI46_24780 in Serratia liquefaciens MT49

Annotation: glycosyltransferase family 4 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF13579: Glyco_trans_4_4" amino acids 17 to 177 (161 residues), 30.4 bits, see alignment E=1.4e-10 PF13439: Glyco_transf_4" amino acids 17 to 181 (165 residues), 71.2 bits, see alignment E=3.4e-23 PF00534: Glycos_transf_1" amino acids 192 to 337 (146 residues), 102 bits, see alignment E=8.2e-33 PF13692: Glyco_trans_1_4" amino acids 208 to 337 (130 residues), 88 bits, see alignment E=2.2e-28

Best Hits

KEGG orthology group: K02844, UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC: 2.4.1.-] (inferred from 96% identity to spe:Spro_4833)

Predicted SEED Role

"UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG (EC 2.4.1.-)" in subsystem LOS core oligosaccharide biosynthesis (EC 2.4.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-

Use Curated BLAST to search for 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>IAI46_24780 glycosyltransferase family 4 protein (Serratia liquefaciens MT49)
MKAFRLAIVRQKYRPDGGAERFVSRALEALEQQDLDLNVITREWQGDANPNWHIHLCNPL
KFGRISRERGFADAARALWQKERFDLVQSHERIPGCDIYRAGDGVHRRWLLQRARLLPEW
RRKWLFSNRYHRYVMCAERAMYAAPELKAVICNAEMIKQEIIDDFGVPADKITVIYNAID
NQKFLPANAEQRQQLRQQYQIPQQAHCLIFVGSGFERKGLAAAIRAVAATDSYLLVVGKD
KAEKRYQALAQSLGCSERVRFMGVQKQTLPFYQAADALLLPTLYDPFPNVILEAMSCGLP
VITSTTCGGAEFITQGQNGFVTDALDVPALIEAITALPRQAQGSTMGEAARLRIMSATPA
HLSEQLISLYNRLLD