Protein Info for IAI46_24295 in Serratia liquefaciens MT49

Annotation: MHS family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 26 to 54 (29 residues), see Phobius details amino acids 66 to 86 (21 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 121 to 145 (25 residues), see Phobius details amino acids 165 to 188 (24 residues), see Phobius details amino acids 200 to 218 (19 residues), see Phobius details amino acids 250 to 271 (22 residues), see Phobius details amino acids 291 to 313 (23 residues), see Phobius details amino acids 322 to 340 (19 residues), see Phobius details amino acids 346 to 370 (25 residues), see Phobius details amino acids 385 to 405 (21 residues), see Phobius details amino acids 411 to 432 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 229 (206 residues), 86.5 bits, see alignment E=1.9e-28 amino acids 270 to 440 (171 residues), 40.8 bits, see alignment E=1.4e-14 PF07690: MFS_1" amino acids 30 to 278 (249 residues), 61.7 bits, see alignment E=6.1e-21 amino acids 284 to 436 (153 residues), 54.5 bits, see alignment E=9.3e-19 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 31 to 425 (395 residues), 499.5 bits, see alignment E=3.9e-154

Best Hits

Swiss-Prot: 83% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to spe:Spro_4745)

Predicted SEED Role

"Inner membrane metabolite transport protein YhjE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>IAI46_24295 MHS family MFS transporter (Serratia liquefaciens MT49)
MQASIAPTLDADDASTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDP
TTATLQSLATFAVAFVARPIGSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYET
IGIFAPILLALARFGQGLGLGGEWGGAALLATENAPARKRALYGSFPQLGAPIGFFFANG
TFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
GTLLSKHLKVTILGTFIMLATYTLFYLMTVYSMTYGTTPQPLGLGYSRNSFLWMLMVAVI
GFGVMVPIAGLLADAFGRRKTMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMG
LTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPYIATWLATHYGLFYVGLYLAA
MASLTLIALLLMKETRDKSL