Protein Info for IAI46_24260 in Serratia liquefaciens MT49

Annotation: autotransporter outer membrane beta-barrel domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1033 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF00082: Peptidase_S8" amino acids 74 to 411 (338 residues), 154.8 bits, see alignment E=4.7e-49 TIGR02601: autotransporter-associated beta strand repeat" amino acids 490 to 521 (32 residues), 28.9 bits, see alignment (E = 7.3e-11) PF12951: PATR" amino acids 491 to 520 (30 residues), 35.9 bits, see alignment (E = 9.4e-13) TIGR01414: outer membrane autotransporter barrel domain" amino acids 555 to 1033 (479 residues), 268.7 bits, see alignment E=1e-83 PF03797: Autotransporter" amino acids 763 to 1013 (251 residues), 221.5 bits, see alignment E=2.5e-69

Best Hits

KEGG orthology group: K12685, subtilase-type serine protease [EC: 3.4.21.-] (inferred from 95% identity to spe:Spro_4737)

Predicted SEED Role

"Extracellular serine protease precursor (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1033 amino acids)

>IAI46_24260 autotransporter outer membrane beta-barrel domain-containing protein (Serratia liquefaciens MT49)
MKQSAGNNKPALAPTWKLNALLCALLAAGGAQAATYTEGGKSGDPASWRSNEFNANWGLG
AIHADEAYAAGYTGKGQKVGIFDTPVNQHPEFAGDGKLTNVVTEGYRAYTDPHREGIKAG
DRFYFDGTFHFYSGSQGQLSNHGVHVAGISGANRDGTGMHGVAFDSQIISVDNDNDGPAY
GEFLGLDGSVTNAGWQAMINNGVRVINNSWGVSIPDFLSDNGKKPDALHFELKDAQEQFD
QVKPLLGSLAGAGYQGAIDAARKNILVLFAAGNDGNYNQPDVISGLAYFVPDIAPNWLSV
ASVAQDDASTNSVPYTISSFSSRCGYTASFCVSSPGSKIYSTVANGSDPNQLVSDYGNKN
GTSMATPHVTGAVAVLLQRFPYMTSAQIADVLKTTATDMGAPGIDALYGWGMINLGKAIN
GPGMFYTVDDIPEEFRIPDPTGVAYGSSQFVANIPGMGAIIDEGTLHARVCDDYHCSLEV
YSNDINGHGGLTKEGQGALVLTGNNTYSGPTWVNTGLLAVNGSVTSDVTVQSAGVLGGSG
TLGSLTARSGGTVAPGNSIGTLNVTRDVRFEPGSRYAVEVAPNGQSDRIQSNGSATIGGG
EVTVSLENSSNLLSQNEVRSLLGQQYNILTAQQGIRGQFDSVAPNYLFLGTGLTYQPNQV
TLNVGRNDTSFASVAATQNERAVAAAADALAAGNPVFESILNAGSTGEARQAFRQLSGQI
HADIASAQVNDSRYLRDALNGRLRQAEGLATSPDIKADDDGGAWAQLLGAWDHASGDANA
TGYQASTYGVLVGLDSALADEWRLGVATGYTRTSLDGGYGSNADSDNYHLAVYGGKQFGE
LALRAGGGYTWHRFDTSRSVNYGMQSDRETAKYSARTEQVFAEAGYSIKAAWVNLEPFAN
LAYINFQNNGIAEDGGAAALHGDKQHTDATVSTLGLRADTEWQASKTTAVALRSELGWQH
QYGDLDRGTGLKFNGGSSPFVVNSVSASRDGAVLKASAEVAVNKNATLSLGYGGLLSQNY
QDNSVNAGFTWKF