Protein Info for IAI46_24205 in Serratia liquefaciens MT49

Annotation: 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 95% identical to RSMJ_SERP5: Ribosomal RNA small subunit methyltransferase J (rsmJ) from Serratia proteamaculans (strain 568)

KEGG orthology group: None (inferred from 95% identity to spe:Spro_4700)

MetaCyc: 78% identical to 16S rRNA m2G1516 methyltransferase (Escherichia coli K-12 substr. MG1655)
RXN0-6731 [EC: 2.1.1.242]

Predicted SEED Role

"rRNA small subunit methyltransferase J"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.242

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>IAI46_24205 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ (Serratia liquefaciens MT49)
MSVCLLCEEGADPGALSILAERWQLVSDDDATMALVLTPERLELRKRDEPKLGAIYVDFI
SGTMAHRRRFGGGRGEAVAKAVGIKGNYRPNVVDATAGLGRDAFVLASLGCRVRMLERNP
VVAALLDDGLQRGYQDAEIGPWLRERMTLLHASSLTALAELDSPPEVVYLDPMYPHKQKS
ALVKKEMRVFQSLVGSDDDADGLLEPARRLATKRVVVKRPDYAPPLANVPAHAASTTKSH
RFDIYMPYPLHT