Protein Info for IAI46_24145 in Serratia liquefaciens MT49

Annotation: NAD(P)/FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07992: Pyr_redox_2" amino acids 4 to 163 (160 residues), 38.9 bits, see alignment E=2.8e-13 PF03486: HI0933_like" amino acids 4 to 392 (389 residues), 523.6 bits, see alignment E=1.3e-160 PF01134: GIDA" amino acids 5 to 36 (32 residues), 22.1 bits, see alignment (E = 2.9e-08) PF00890: FAD_binding_2" amino acids 5 to 49 (45 residues), 31 bits, see alignment 6.4e-11 PF12831: FAD_oxidored" amino acids 5 to 138 (134 residues), 33.5 bits, see alignment E=1.2e-11 TIGR00275: flavoprotein, HI0933 family" amino acids 6 to 392 (387 residues), 430.7 bits, see alignment E=2.6e-133 PF13450: NAD_binding_8" amino acids 8 to 39 (32 residues), 24.6 bits, see alignment (E = 9.9e-09)

Best Hits

Swiss-Prot: 80% identical to YHIN_ECOLI: Uncharacterized protein YhiN (yhiN) from Escherichia coli (strain K12)

KEGG orthology group: K07007, (no description) (inferred from 98% identity to srs:SerAS12_4790)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>IAI46_24145 NAD(P)/FAD-dependent oxidoreductase (Serratia liquefaciens MT49)
MEQFDVVVIGAGAAGMFCAAQAGQLGCRVLLLDNGKKPGRKILMSGGGRCNFTNMYTEPA
AYLSNNPHFCKSALARYTQWDFIDLINRHGIAYHEKTLGQLFCDDSAQQVVELLVKECEQ
GQVTTRLRSEVLGVEKTAEGFELALNGEKVSARSLVVASGGLSMPGLGATPFGYKLAEQF
GLKVLPTRAALVPFTLHKPLLEHLQTLSGVSVPAVITAENGVSFRESILFTHRGLSGPAV
LQLSSYWQPGEFVSVNLLPTLDLAGFLNEQRQAHPNQSLKNTLALHLPKRLVECLQTLGQ
LPEATLKQLNPTQQAALVETLQNWRVQPNGTEGYRTAEVTLGGVDTKELSSKTMEAAKVP
GLYFIGEVVDVTGWLGGYNFQWAWSSAWACAQALAAQKQ