Protein Info for IAI46_23925 in Serratia liquefaciens MT49

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 1 to 475 (475 residues), 564.3 bits, see alignment E=1.1e-173 PF08323: Glyco_transf_5" amino acids 2 to 234 (233 residues), 248.8 bits, see alignment E=1.6e-77 PF13439: Glyco_transf_4" amino acids 107 to 221 (115 residues), 34.2 bits, see alignment E=6.6e-12 PF00534: Glycos_transf_1" amino acids 288 to 448 (161 residues), 51.9 bits, see alignment E=1.7e-17 PF13692: Glyco_trans_1_4" amino acids 293 to 438 (146 residues), 36.5 bits, see alignment E=1.4e-12

Best Hits

Swiss-Prot: 97% identical to GLGA_SERP5: Glycogen synthase (glgA) from Serratia proteamaculans (strain 568)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 97% identity to spe:Spro_4644)

MetaCyc: 75% identical to glycogen synthase (Escherichia coli K-12 substr. MG1655)
Starch synthase. [EC: 2.4.1.21]

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>IAI46_23925 glycogen synthase GlgA (Serratia liquefaciens MT49)
MQVLHVCSEMFPLLKTGGLADVVGALPAAQIAEGGDVRVLLPAFPDVRNGIPDSVLVAEI
DSFAGRVGLRYGTYHGVGIYLIDAPWLYERPGSPYHDQSMNAYSDNHRRFALLGWMACEL
AKGLDRYWRPQIVHAHDWHAGLACAYLAANGHPARSIFTVHNLAYQGLFSAHHVAELWLP
PSFYNVYGLEFYGQMSFLKAGLYYADHITAVSPTYAREITRPEFGYGMEGLLQERQHQGR
LSGILNGVDDKIWDPSHDPRLTARYDADDLKNKVNNKLHLQKAMGLKVDESLPVFAVVSR
LTSQKGLDLVLEALPALLEQGGQLALLGAGDAVLQQAFLAAAADYPEQVGVQIGYHEAFS
HRIIGGADVIMVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVVDCALENLADGSASG
FVFDDCDATALGNAIRRAMVLWSRPKHWRHVQRHAMSVDFGWQVAAKEYLSLYSRHI