Protein Info for IAI46_23630 in Serratia liquefaciens MT49

Annotation: PTS lactose/cellobiose transporter subunit IIA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02255: PTS_IIA
  • amino acids 11 to 103 (93 residues), 100.1 bits, E=3e-33

Best Hits

Swiss-Prot: 45% identical to PTQA_ECOL6: PTS system N,N'-diacetylchitobiose-specific EIIA component (chbA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02759, PTS system, cellobiose-specific IIA component [EC: 2.7.1.69] (inferred from 95% identity to spe:Spro_4590)

MetaCyc: 45% identical to N,N'-diacetylchitobiose-specific PTS enzyme IIA component (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-155B [EC: 2.7.1.196]

Predicted SEED Role

"PTS system, cellobiose-specific IIA component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

• Aminosugars metabolism
• Ascorbate and aldarate metabolism
• Fructose and mannose metabolism
• Galactose metabolism
• Glycolysis / Gluconeogenesis
• Nucleotide sugars metabolism
• Starch and sucrose metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.196 or 2.7.1.69

Protein Sequence (112 amino acids)

>IAI46_23630 PTS lactose/cellobiose transporter subunit IIA (Serratia liquefaciens MT49)
MTEISPDFESTIMELLVFSGGARSSALMALQQARAGDFTASAKHMAESKQSVKKAHLIQT
QLIGMDEGCGKLAINLITVHAQDHLMNAMVIQDLADDMIELYRRQAQMEVRA