Protein Info for IAI46_23460 in Serratia liquefaciens MT49

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 TIGR00484: translation elongation factor G" amino acids 1 to 703 (703 residues), 1281.3 bits, see alignment E=0 TIGR00231: small GTP-binding protein domain" amino acids 9 to 187 (179 residues), 110.2 bits, see alignment E=9.1e-36 PF00009: GTP_EFTU" amino acids 9 to 288 (280 residues), 212.3 bits, see alignment E=1.2e-66 PF03144: GTP_EFTU_D2" amino acids 331 to 398 (68 residues), 65.3 bits, see alignment E=1.4e-21 PF14492: EFG_III" amino acids 411 to 485 (75 residues), 114.1 bits, see alignment E=6.2e-37 PF03764: EFG_IV" amino acids 486 to 609 (124 residues), 150.8 bits, see alignment E=3.8e-48 PF00679: EFG_C" amino acids 611 to 696 (86 residues), 101.4 bits, see alignment E=5.6e-33

Best Hits

Swiss-Prot: 94% identical to EFG_CROS8: Elongation factor G (fusA) from Cronobacter sakazakii (strain ATCC BAA-894)

KEGG orthology group: K02355, elongation factor G (inferred from 95% identity to cro:ROD_44791)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (704 amino acids)

>IAI46_23460 elongation factor G (Serratia liquefaciens MT49)
MARTTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
ITITSAATTAFWSGMAKQFEPHRVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQ
PQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKSRLGANPVPLQLAIGAEEKFT
GVVDLVKMKAINWNEADAGVTFEYEDIPADMQELAEEWRQNLVESAAEASDELMDKYLGG
EELTEEEIKTALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPIDVPAINGILD
DGKDTPAERHASDEEPFAALAFKIATDPFVGNLTFFRVYSGIVNSGDTVLNSVKAARERL
GRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPNHVIILERMEFPEPVISVAV
EPKTKADQEKMGLALGRLAKEDPSFRVWTDEESGQTIIAGMGELHLDILVDRMKREFNVE
ANVGKPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDI
KGGVIPTEYIPAIDKGLQEQLKSGPLAGYPVVDLGVRLHFGSFHDVDSSELAFKLAASIA
FKDGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGQLKGQESNATGVQIHAEVPL
SEMFGYATQLRSLTKGRASYSMEFLKYDDAPNNVAQAVIEARGK