Protein Info for IAI46_23070 in Serratia liquefaciens MT49

Annotation: maltose ABC transporter permease MalF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 47 to 65 (19 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 291 to 317 (27 residues), see Phobius details amino acids 327 to 351 (25 residues), see Phobius details amino acids 382 to 403 (22 residues), see Phobius details amino acids 428 to 450 (23 residues), see Phobius details amino acids 496 to 517 (22 residues), see Phobius details PF20872: MalF_N_TM" amino acids 21 to 68 (48 residues), 81.1 bits, see alignment 5.7e-27 PF14785: MalF_P2" amino acids 107 to 271 (165 residues), 207.8 bits, see alignment E=1.5e-65 PF00528: BPD_transp_1" amino acids 309 to 512 (204 residues), 69.7 bits, see alignment E=4.1e-23

Best Hits

Swiss-Prot: 82% identical to MALF_YERPE: Maltose/maltodextrin transport system permease protein MalF (malF) from Yersinia pestis

KEGG orthology group: K10109, maltose/maltodextrin transport system permease protein (inferred from 96% identity to srs:SerAS12_4576)

MetaCyc: 77% identical to maltose ABC transporter membrane subunit MalF (Escherichia coli K-12 substr. MG1655)
ABC-16-RXN [EC: 7.5.2.1]; 7.5.2.1 [EC: 7.5.2.1]; 7.5.2.1 [EC: 7.5.2.1]

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, permease protein MalF" in subsystem Maltose and Maltodextrin Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>IAI46_23070 maltose ABC transporter permease MalF (Serratia liquefaciens MT49)
MQLAHAGLPARKKSKWWQSDVLKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAG
LYVFANRRAYAWRYVYPGIAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQ
FQTGKTFTFGLYPAENQRWRLQLTHPDSDQKLISEPFSFDASAPQTLKLTEESAEPAGER
ATLRVITQNRQALSQLVALLPSGGELRMSSLRQFSGTTPLYALDKESNTLTDQQTHTQYR
PNPDIGFYQAVNAEGNWAKETLSPGYTVTIGWKNFLRVLQDEGIKKPFVSIFIWTIVFSV
MTVILTVAVGMVLACVVQWEALKGKAVYRVMLILPYAVPSFISILIFKGLFNQSFGEINM
MLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAT
PMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD