Protein Info for IAI46_22980 in Serratia liquefaciens MT49

Annotation: RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 PF04542: Sigma70_r2" amino acids 3 to 65 (63 residues), 33.6 bits, see alignment E=4.1e-12 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 3 to 145 (143 residues), 62.2 bits, see alignment E=2.4e-21 PF08281: Sigma70_r4_2" amino acids 92 to 144 (53 residues), 53.7 bits, see alignment E=2e-18 PF04545: Sigma70_r4" amino acids 99 to 144 (46 residues), 35 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 91% identity to spe:Spro_4455)

Predicted SEED Role

"RNA polymerase sigma-54 factor RpoN" in subsystem Flagellar motility or Flagellum or Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (162 amino acids)

>IAI46_22980 RNA polymerase sigma factor (Serratia liquefaciens MT49)
MGQYLSRLWRYGLVLTHRRDVADDLVQATCVRALERAAQFAVGTRMDRWLFSILHSIWLN
EVRSQHIRQGQGFVDVDELAGAENGEQPIWANEVMQRVNQLPEAQRNTLFLVYVEELSYR
EAAEVLGVPIGTIMSRLAAARLRLANDSLLQTRTPQVKGEQS