Protein Info for IAI46_22815 in Serratia liquefaciens MT49

Annotation: amino acid adenylation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1314 transmembrane" amino acids 128 to 146 (19 residues), see Phobius details amino acids 238 to 258 (21 residues), see Phobius details PF00668: Condensation" amino acids 3 to 443 (441 residues), 243 bits, see alignment E=1.4e-75 PF00501: AMP-binding" amino acids 464 to 818 (355 residues), 343.3 bits, see alignment E=4e-106 TIGR01733: amino acid adenylation domain" amino acids 485 to 892 (408 residues), 478.2 bits, see alignment E=9.8e-148 PF13193: AMP-binding_C" amino acids 877 to 951 (75 residues), 38.9 bits, see alignment 3.4e-13 PF00550: PP-binding" amino acids 980 to 1042 (63 residues), 47.4 bits, see alignment 4.7e-16 PF00975: Thioesterase" amino acids 1088 to 1187 (100 residues), 64.4 bits, see alignment 4.6e-21

Best Hits

KEGG orthology group: None (inferred from 61% identity to ebi:EbC_06320)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1314 amino acids)

>IAI46_22815 amino acid adenylation domain-containing protein (Serratia liquefaciens MT49)
MSAYSLTTVQQAVWLDQTLNPDIPLYNVGCLWRVEREISFPLFKEAIQQVQQRHDALQTT
LKETPQGIIQQPLSQRSIELHYTDFSQQEDAASLAQNHLRDMFIQPYQLYEDLLWRCHLT
KIDDSTTLWLLASHHLIADGTSISLLSRMIMDRYKQLKAGDKSEASKSHYGDFVVSDRAY
LQSLRYQRDRDWWLERFATAPASVLERRPHYTEQQAYPSSQIIKRLPRERFLRLEQYAAQ
HGGSAMHFMVALLASWFARIWQMDNVTLGVPVHNRSTQDHKQTLGMFSSMIPLNIDVDLQ
QPFHHLLRQVGSELRRCYRHQRFPIAELNRQLNLHQQGRRQLFDISFSLEAFPTDIELEG
SQFKVENIHHGYEQLPLGIYLRHYHPSDDPLLEFNLNQAWFSDKDGERIASRILQMLDSL
LEGDPDLPLGQLPLLLPVERQQIFGEWNHTQQSWAMPQGIHQFLEQQVLRTPNAPALCYE
QQQVSYLQLNQQANQFAGFLRQQGIQPDDRIAVCVNRSPEMVMALYAILKSGAAYVPIDP
DYPQDRLRHMLQDCGAKFVLIDEAGEQALHSIHDVVIPRLHLQHDSHRWQQGATENLAPL
ASDPQRSLAYVIYTSGSTGKPKGVMNEHRGVINRLLWTQQAYPLTHDDVILQKTPFSFDV
SVWEFFWPLMVGAQLVIAKPGGHQDPDYLSACIAQNRVTTLHFVPSMLQLFLRHGEMTQC
ASLRRILCSGEALPLATVQRCLQQLPQAQLYNLYGPTEAAVDVSSWQCLPNDERPLVPIG
KPIANTQLHILDHQLQPLPPGVAGELHIGGIQVARGYLNRPELNAERFIADPFSPESDAR
LYKTGDLARWLPDGNIEYLGRNDFQVKIHGVRIELGEIEQQLRQCTGVEDAAILAKEDGQ
GGKRLIAYVVAPDENVHSTQWRQQLQQQLPDFMVPSSFVRLKALPLSPNGKLDRKALPAP
APVTQVSLRYEAPQTALEKQLAELWSELLGVAQIGLDDDFFELGGHSLHAIQLLVKLKRR
GYPVVIKTLFAHPSLRAQAQALASEKDSDIDAPITAAPLQQLLARLNQTSLAFKQVLRLN
RTQAANDIWMVHPAVTGCDIYHDLASSLEGEFNAFGINNYNLFMPTPITSLRELASYYLG
HMKLAPSRPVRLLGWSLGGLIALEMAAQLESRGFSDVQVFLLDTFYQTAFQLRSEPGLLA
AMLAMLGIDGEAAARALRAEPTELSLNKERLSAPLRHARITLFKATEDVNLSMNDQGDGR
ELLAIADNGLSSISPSLQIQPLACNHHSIIFSHEEIGRVLRESTRAPAASTGIR