Protein Info for IAI46_22520 in Serratia liquefaciens MT49

Annotation: DgaE family pyridoxal phosphate-dependent ammonia lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 TIGR01437: uncharacterized pyridoxal phosphate-dependent enzyme" amino acids 4 to 366 (363 residues), 589 bits, see alignment E=1.5e-181 PF03841: SelA" amino acids 14 to 270 (257 residues), 53.8 bits, see alignment E=1.7e-18 PF01053: Cys_Met_Meta_PP" amino acids 132 to 226 (95 residues), 29.3 bits, see alignment E=3.4e-11

Best Hits

KEGG orthology group: K01042, L-seryl-tRNA(Ser) seleniumtransferase [EC: 2.9.1.1] (inferred from 97% identity to spe:Spro_4375)

Predicted SEED Role

"D-Glucosaminate-6-phosphate ammonia-lyase (EC 4.3.1.-)" (EC 4.3.1.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.9.1.1

Use Curated BLAST to search for 2.9.1.1 or 4.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (372 amino acids)

>IAI46_22520 DgaE family pyridoxal phosphate-dependent ammonia lyase (Serratia liquefaciens MT49)
MSSIYEKYNLKQVINTSGRMTALGVSTPRQDVIDAVDYGMNHYFEIKDLVDKTGAYIANL
LNVESAVVVSCASAGIAQSVAALIVKDNANLLVNLHSAPITVPREIVLPRGHNVNFGAPV
DTMVALGGGKVVEAGYANECSAEQLEACITPQTAAILYIKSHHCVQKSILSVEQAVVVAR
KHNLPLIVDAAAEEDLLCYYQMGADLVVYSGAKAIEGPTSGLVIGKKQYVEWVKLQTGGI
GRAMKVGKDGILGLTQAIESYLRLEKTTGQQMVERMTPFIDSLNTLTGISAKTVWDSAGR
DIARAEITFDEAVLGWSTYDIVQALKTGEIAIYFRGYKANEGKIEVDVRSVDQQQLMTVF
TCIKNLFTEKQA