Protein Info for IAI46_22380 in Serratia liquefaciens MT49

Annotation: cell division protein ZapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF03969: AFG1_ATPase" amino acids 5 to 370 (366 residues), 505.7 bits, see alignment E=3.5e-156

Best Hits

Swiss-Prot: 68% identical to ZAPE_ECO57: Cell division protein ZapE (zapE) from Escherichia coli O157:H7

KEGG orthology group: K06916, (no description) (inferred from 95% identity to spe:Spro_4350)

Predicted SEED Role

"ATPase, AFG1 family" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>IAI46_22380 cell division protein ZapE (Serratia liquefaciens MT49)
MQAQSPLSRYQRLLAAGEYQADEVQRQAVTQLDHIYQALQQIPAVSAPAGGLRGKLSRLL
GKSSETAKQRPVQGLYMWGGVGRGKTWLMDMFFHSLPGDRKLRLHFHRFMLRVHEELTEL
QGQENPLEIIADGFKAQTDVLCFDEFFVSDITDAMLLATLLQALFARGITLVATSNIPPD
DLYRNGLQRARFLPAIDLINEYCDVMNVDAGIDYRLRTLTQAHLYLTPLDEQTRQTMDQM
FVKLAGKKGEAAPVLQINHRPLQVIHAVDGVLAVDFHTLCEEARSQLDYIALSRLYHSVI
LYNVRVMGPLKENTARRFLALVDEFYERHVKLVIAAEASMFEIYQGERLKFEYQRCLSRL
QEMQSEEYLKLPHLP