Protein Info for IAI46_22095 in Serratia liquefaciens MT49

Annotation: ferrichrome porin FhuA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF07715: Plug" amino acids 71 to 174 (104 residues), 92 bits, see alignment E=3.4e-30 TIGR01783: TonB-dependent siderophore receptor" amino acids 73 to 729 (657 residues), 492.7 bits, see alignment E=9.7e-152 PF00593: TonB_dep_Rec" amino acids 247 to 700 (454 residues), 236.7 bits, see alignment E=9.7e-74

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 52% identity to spe:Spro_3979)

Predicted SEED Role

"Ferric hydroxamate outer membrane receptor FhuA" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (731 amino acids)

>IAI46_22095 ferrichrome porin FhuA (Serratia liquefaciens MT49)
MKTIRRLIIKQPNLFMLLAGICTSSLAYAAGENESVITVYGEGNTAEEAIGSNGTYAAKQ
SVTATKTSTPLIKTPQSISVITQEELQTKRPATIKNALNYTPGVMTGNSGSSSIFDSVMI
RGFNNVSQNIYLDGLKLQGDMYADSKVDPYFLQRVEVLRGPASVLYGKSNPGGVISSVSK
RPQKQPLHELQLQAGNHHEWKTQFDFSDALDDEEALAYRLTGNYYEAHSQQKGEREKRYA
IAPSLLWQPSDKTSLLFQLSLQNEPRTGYYGWLPSEGTLTSGEFGKLSPSFNEGEPSYNR
FERQQRTVGYQLDHAFNDTWSFHQAVRYQHTKVNWRSIYGNGLCNPMTCMGVAPQQYGTT
LSRATMVSDERLNGLTTDTRLEGKLNAGSWRHTLLMGIDYSQLRNDLQNKMGSAAPLNLV
NPQYGNHDVLYFGDTHTINKNHQLGTYLQDQAEWQNWVFTLGGRFDHSVVKTHESSNMTG
SESSSSITDNEFTWRGGVNYVFNNGIAPYVSYSESFEPNSGNSLSGQAFKPSRGKQYEAG
IKFIPDNAPVSASIAAFQLTKDNNLRRDALNPYYNVQEGKIRSRGIEIEGKAALTYNLNL
IASYTYTHAEFRDNSGNNGHTPAMVPKHMANLWTDYTFNQGWLNGLSLGGGARYVSSTPG
DDGNNFKVPSYTVFDTAIKYQLDDIPGLENAEIALNVNNLFDKHYVSSCFTNNTCSWGAE
RQILTTLTLHW