Protein Info for IAI46_22080 in Serratia liquefaciens MT49

Annotation: undecaprenyl-diphosphate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 50 to 69 (20 residues), see Phobius details amino acids 93 to 111 (19 residues), see Phobius details amino acids 123 to 141 (19 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 225 to 247 (23 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 10 to 266 (257 residues), 332.1 bits, see alignment E=1.3e-103 PF02673: BacA" amino acids 10 to 268 (259 residues), 283.4 bits, see alignment E=9.9e-89

Best Hits

Swiss-Prot: 97% identical to UPPP_SERP5: Undecaprenyl-diphosphatase (uppP) from Serratia proteamaculans (strain 568)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 100% identity to srs:SerAS12_4403)

MetaCyc: 83% identical to undecaprenyl pyrophosphate phosphatase (Escherichia coli K-12 substr. MG1655)
RXN-11776 [EC: 3.6.1.68]; Undecaprenyl-diphosphatase. [EC: 3.6.1.68, 3.6.1.27]

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.27 or 3.6.1.68

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>IAI46_22080 undecaprenyl-diphosphate phosphatase (Serratia liquefaciens MT49)
MADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAV
VVMFWRRLFGLIGIHFGGKPVEHEGKTAGRLKLGHILLAMIPAVVLGLLLHDFIKSLFAP
KNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFMIGCFQCLALWPGFSRSGSTI
AGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVAL
IAIKTFLSLIKRISFVPFAIYRFIVAAVVYMVFM