Protein Info for IAI46_22065 in Serratia liquefaciens MT49

Annotation: inorganic triphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 PF01928: CYTH" amino acids 4 to 196 (193 residues), 118.9 bits, see alignment E=1.2e-38

Best Hits

KEGG orthology group: None (inferred from 94% identity to srs:SerAS12_4400)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (435 amino acids)

>IAI46_22065 inorganic triphosphatase (Serratia liquefaciens MT49)
MTVEIELKFIATPDAVAALPQQLAAWPHQHSAPQKLTNIYFETADNFLRSQDMGLRIRGF
DDSYEMTIKTAGKVVAGLHQRPEYNVAITTPELALERFPADIWPQGCDVDALQQALQPLF
RTDFVREKWVVTYGKSEIEVGLDQGEVSAGELSEALCEIELELKTGNTDDLLALANELAM
HGGLRQGNLSKAARGYHLAQGNAPRERRPLTVLKPAAKSSVEQGMVASFELGLSHWQYHE
ELWLRGDTQARRSVMEAIALIRQALVIFGGLVPRKASADLRARLTALEPLLIDKSTQPQV
LCYSAEYLQCKLALTSWLVTGAWKPFIDAKAQTKLDGSFKRFSDIMLGRSAAELKEAFTR
TLNEDEYEEQLPRLTRQVSAFILLSGAYPDDETGPYIESWRELQQALAERRQGWYESSRK
QALSHAPFWLNGALR