Protein Info for IAI46_21675 in Serratia liquefaciens MT49
Annotation: aminoimidazole riboside kinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 63% identical to SCRK_KLEPN: Fructokinase (scrK) from Klebsiella pneumoniae
KEGG orthology group: K00847, fructokinase [EC: 2.7.1.4] (inferred from 94% identity to spe:Spro_4203)MetaCyc: 63% identical to fructokinase (Klebsiella pneumoniae)
Fructokinase. [EC: 2.7.1.4]
Predicted SEED Role
"Fructokinase (EC 2.7.1.4)" in subsystem Fructose utilization or Mannitol Utilization or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Sucrose utilization or Sucrose utilization Shewanella (EC 2.7.1.4)
MetaCyc Pathways
- superpathway of anaerobic sucrose degradation (17/19 steps found)
- heterolactic fermentation (15/18 steps found)
- sucrose degradation III (sucrose invertase) (4/4 steps found)
- D-sorbitol degradation I (3/3 steps found)
- mannitol cycle (4/5 steps found)
- sucrose degradation II (sucrose synthase) (4/5 steps found)
- sucrose degradation IV (sucrose phosphorylase) (3/4 steps found)
- sucrose degradation I (sucrose phosphotransferase) (2/3 steps found)
- sucrose degradation VII (sucrose 3-dehydrogenase) (1/4 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.4
Use Curated BLAST to search for 2.7.1.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (309 amino acids)
>IAI46_21675 aminoimidazole riboside kinase (Serratia liquefaciens MT49) MVNRVWVLGDAVVDLVPENSNSYLKCPGGAPANVAVGIARLGGDSAFIGRVGQDSFGTFL QQVLSEEQVDIGHMFQDPDHHTSTVVVDLDLSGERSFTFMVNPSADLFLQPEDLPEFNAD EWLHVCSIALSQEPSRSTTFAAMENIKAAGGWVSFDPNIREEVWRQPDALRTCLQKALLL ADVVKISLEELSFISNIGELESAIDWMMQRYPLRLLLVTLGGNGVCVHDGKQIRHFRAPT ITPVDTTGAGDAFVAGLLAALAQIGALPQEEQWPAVIAQAQACGALATTAKGAMTALPHA DELRAFLRR