Protein Info for IAI46_21375 in Serratia liquefaciens MT49

Annotation: SprT family zinc-dependent metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 170 PF10263: SprT-like" amino acids 21 to 115 (95 residues), 80 bits, see alignment E=1.1e-26 PF17283: Zn_ribbon_SprT" amino acids 125 to 164 (40 residues), 40 bits, see alignment 3.2e-14

Best Hits

Swiss-Prot: 92% identical to SPRT_SERP5: Protein SprT (sprT) from Serratia proteamaculans (strain 568)

KEGG orthology group: None (inferred from 94% identity to srr:SerAS9_4226)

Predicted SEED Role

"Protein sprT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (170 amino acids)

>IAI46_21375 SprT family zinc-dependent metalloprotease (Serratia liquefaciens MT49)
MNKVRIPIALQQAVMRCLREKLLLARQHFSVEFPEPKVVYQQRGTSAGTAWLQAWEIRLN
PVLLMENQQPFIDEVVPHELAHLLVFRQFGRVAPHGREWRWMMESVLQVPASRTHQFEIA
SVQSKTFPYLCRCQQHQLTVRRHNRVLRGESEYRCRQCGEKLKFIAGEPV