Protein Info for IAI46_21175 in Serratia liquefaciens MT49

Annotation: Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01497: Peripla_BP_2
  • amino acids 43 to 276 (234 residues), 139.5 bits, E=6.3e-45

Best Hits

Swiss-Prot: 57% identical to FHUD_ECOLI: Iron(3+)-hydroxamate-binding protein FhuD (fhuD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 92% identity to srr:SerAS9_4185)

MetaCyc: 57% identical to iron(III) hydroxamate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.16

Protein Sequence (302 amino acids)

>IAI46_21175 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD (Serratia liquefaciens MT49)
MPDSSDFHHDAVRRRLLTAMALSPLLFSLPSQAAATPPDLARIVALEWLPVELLLALGIT
PLAVADIHNYNLWVEEPKMPASVIDVGQRTEPNLELLQQLRPSLLLLSQGYGPTPQKLAP
IGPTMSFGFNDGSGKPLTVGRKSLVQLAQRLGLEARAEQHLIQFDRFIQDARQRLQSYSR
QPLLLFSLLDTRHALVIGQKSLFQEVMDQLGIQNAWEGETNFWGTAVVGIERLTAVKNAR
AIYLDHGNQAMMEKVSSTPLWQALPFVRQNQLRQVPAVWFYGATLSAMRFCHLLEQAQES
YS