Protein Info for IAI46_20785 in Serratia liquefaciens MT49

Annotation: MHS family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 40 to 59 (20 residues), see Phobius details amino acids 65 to 88 (24 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 131 to 155 (25 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 201 to 220 (20 residues), see Phobius details amino acids 266 to 284 (19 residues), see Phobius details amino acids 290 to 311 (22 residues), see Phobius details amino acids 321 to 339 (19 residues), see Phobius details amino acids 345 to 364 (20 residues), see Phobius details amino acids 385 to 406 (22 residues), see Phobius details amino acids 412 to 433 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 31 to 233 (203 residues), 75.8 bits, see alignment E=4.9e-25 amino acids 234 to 441 (208 residues), 49.6 bits, see alignment E=4.6e-17 PF07690: MFS_1" amino acids 34 to 399 (366 residues), 108.5 bits, see alignment E=5.4e-35 amino acids 271 to 431 (161 residues), 45.7 bits, see alignment E=6.7e-16 PF13347: MFS_2" amino acids 66 to 371 (306 residues), 31.4 bits, see alignment E=1.1e-11

Best Hits

KEGG orthology group: None (inferred from 97% identity to srr:SerAS9_4110)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>IAI46_20785 MHS family MFS transporter (Serratia liquefaciens MT49)
MSTSTTETPTLNLSADDSAAHPPKTGRLAAASSIGTALEWYDFTVYNIMAALIFNHVFFP
SFDPLVGTILAFSTYAVGYVSRPIGGIVFGHLGDVLGRRFVLVTTLVIMGVTTALMGLLP
GYASWGIWSPLLLVTLRFIQGIALGGEWAGAVLLSMEHGKPHQRGRNASFAQVGPSCGTL
IGTGLITLVTVAMSAEDFQQWGWRIPFLLSLVLVVFGLWLRRGVGETPAFLKLEASKDVT
HAPIREVFTQHRRPLLIAGGSRIGSDVLYALVVVFTLTYVTTVLNLPRPLALTATMLGAI
GNAITVPMFGALSDRFGRRPVYIGGALAAMVWAFVFFVLLDSSQPVLICLAVVVGLLIHA
AMYGPQAAFITEQFPTRVRYAGSSLAYTLAGIIGGGFAPLIIASLFKSYDSTLAISAYVV
VALLITLWAVIAAKETAHKPL