Protein Info for IAI46_20560 in Serratia liquefaciens MT49

Annotation: PTS sugar transporter subunit IIA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03610: EIIA-man
  • amino acids 3 to 114 (112 residues), 85.5 bits, E=1.5e-28

Best Hits

Swiss-Prot: 38% identical to YADI_ECOLI: Putative phosphotransferase enzyme IIA component YadI (yadI) from Escherichia coli (strain K12)

KEGG orthology group: K02744, PTS system, N-acetylgalactosamine-specific IIA component [EC: 2.7.1.69] (inferred from 91% identity to spe:Spro_3844)

MetaCyc: 52% identical to AgaF (Escherichia coli O157:H7)
TRANS-RXN-167 [EC: 2.7.1.193]

Predicted SEED Role

"PTS system, N-acetylgalactosamine- and galactosamine-specific IIA component (EC 2.7.1.69)" in subsystem N-Acetyl-Galactosamine and Galactosamine Utilization (EC 2.7.1.69)

KEGG Metabolic Maps

• Aminosugars metabolism
• Ascorbate and aldarate metabolism
• Fructose and mannose metabolism
• Galactose metabolism
• Glycolysis / Gluconeogenesis
• Nucleotide sugars metabolism
• Starch and sucrose metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.193 or 2.7.1.69

Protein Sequence (144 amino acids)

>IAI46_20560 PTS sugar transporter subunit IIA (Serratia liquefaciens MT49)
MPGIVITGHGSFASGLLQAVEQVVGPQQNCVAVNFPEQMSTAQLRGALNAALTEVAQADG
VVFLTDMLGGSPFRCASELADERGDCEVLTGVNMQLAAEMMLERDGLSLDEFREVALACG
KRGLTSLWHERRRVKCEDVQADGI