Protein Info for IAI46_20480 in Serratia liquefaciens MT49

Annotation: lysophospholipid transporter LplT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 16 to 41 (26 residues), see Phobius details amino acids 53 to 73 (21 residues), see Phobius details amino acids 92 to 116 (25 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details amino acids 225 to 247 (23 residues), see Phobius details amino acids 256 to 277 (22 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 371 to 392 (22 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 344 (325 residues), 74.1 bits, see alignment E=5.2e-25

Best Hits

Swiss-Prot: 95% identical to LPLT_SERP5: Lysophospholipid transporter LplT (lplT) from Serratia proteamaculans (strain 568)

KEGG orthology group: K08227, MFS transporter, LPLT family, lysophospholipid transporter (inferred from 95% identity to spe:Spro_3829)

MetaCyc: 78% identical to lysophospholipid transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-294; TRANS-RXN-295; TRANS-RXN-387

Predicted SEED Role

"Lysophospholipid transporter LplT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>IAI46_20480 lysophospholipid transporter LplT (Serratia liquefaciens MT49)
MNPSSNTDSPLLSRSMIAVICAQFLSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVA
TYIILAPFVGQIADSFAKGRVMMVANGLKLAGALVICFGLDPFLGYSLVGVGAAAYSPAK
YGILGEITSGEKLVKANGLMEASTIAAILLGSVAGGILADWHVVAALAVCALVYAAAVIA
NLYIPRLSAAHPATSWTPRAMTRAFFNACVVLWRDGQTRFSLIGTSLFWGAGVTLRFLLV
LWVPVALGIADNATPTLLNAMVAVGIVVGAGAAARFVTLETVKRCMPAGILIGVAVAIFA
LQTTLLSAYAVLLIIGVLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENTAMLLMLG
LYSLAVKVSVPVVGVGIGFGVVFALAIGALWLSQRRAK