Protein Info for IAI46_20215 in Serratia liquefaciens MT49

Annotation: molecular chaperone Skp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03938: OmpH" amino acids 25 to 163 (139 residues), 117.7 bits, see alignment E=2.4e-38

Best Hits

Swiss-Prot: 87% identical to SKP_PECAS: Chaperone protein Skp (skp) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K06142, outer membrane protein (inferred from 98% identity to spe:Spro_3781)

MetaCyc: 67% identical to periplasmic chaperone Skp (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Outer membrane chaperone Skp (OmpH) precursor @ Outer membrane protein H precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (165 amino acids)

>IAI46_20215 molecular chaperone Skp (Serratia liquefaciens MT49)
MKKWLCAAGLGLAMAASAGVQAADKIAVVNVSSIFQQLPARETVAKQLENEFKGRAGELQ
NMERSLQTKMQRLQRDGATMKASDRSKLEKDVMAQREQFSQKAQAFEQDNRRRQMEERNK
ILSRIQDAVKSVASKEGYDVVIDANAVAYAGSSKDITADVLKQVK