Protein Info for IAI46_20170 in Serratia liquefaciens MT49

Annotation: winged helix-turn-helix transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 181 PF12802: MarR_2" amino acids 27 to 86 (60 residues), 50.6 bits, see alignment E=4.3e-17 PF01047: MarR" amino acids 29 to 87 (59 residues), 36.5 bits, see alignment E=9.1e-13 PF13463: HTH_27" amino acids 49 to 94 (46 residues), 36.9 bits, see alignment E=9e-13 PF01022: HTH_5" amino acids 51 to 75 (25 residues), 22.2 bits, see alignment (E = 2.5e-08)

Best Hits

KEGG orthology group: None (inferred from 95% identity to spe:Spro_3772)

Predicted SEED Role

"Transcriptional regulator, MarR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (181 amino acids)

>IAI46_20170 winged helix-turn-helix transcriptional regulator (Serratia liquefaciens MT49)
MTLFDLLERLNSLQRSWLRSHEELESLPPVQLSALYYLARCNHYSNTPMAVAEYLGLTKG
TVSQSLKKLESNGMIARTADEKDRRSVRLKLTDKSRSLMDALFPPAYLQQAQDAMQQDGG
QLLELLTQLLRQLQKQDDNVALFGECHQCRYHQRHDGQPFCGLTQEPLPTSSVNLICREF
A