Protein Info for IAI46_20155 in Serratia liquefaciens MT49

Annotation: lysine decarboxylation/transport transcriptional activator CadC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 transmembrane" amino acids 166 to 188 (23 residues), see Phobius details PF00486: Trans_reg_C" amino acids 25 to 100 (76 residues), 61.7 bits, see alignment E=5.6e-21 PF18500: CadC_C1" amino acids 199 to 330 (132 residues), 242.3 bits, see alignment E=1.3e-76

Best Hits

KEGG orthology group: K03765, transcriptional activator of cad operon (inferred from 87% identity to spe:Spro_3769)

Predicted SEED Role

"Transcriptional activator of cad operon" in subsystem Lysine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (518 amino acids)

>IAI46_20155 lysine decarboxylation/transport transcriptional activator CadC (Serratia liquefaciens MT49)
MQEPVFRVGEWLVTPADNKISRDGRQQTLEPRLIDMLQYFARHPDVVLSRDELIDNVWKR
NIVTNHVVTQSISELRKYLKDGDTNSPEYIITVPKRGYKLAAPVMWCEGDDVATPAVPQV
AVIMHEPEDGSDGSEEDEVAYEPPKPTKTKTPSVTSTTPFYRQSTFWVWLAFLAALSACV
VFVAIATLSQRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTY
STFLVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVNNADSSIMLDKRYFV
TDDNQLKIQEDFLSSLSTALKQPWPPQLQQRLTQLLPNSGPALQQYYQAHQLLIQGDNDS
LTHASNMLADMIKITPNFIYLSAEKALADLLRNSYQPFDGVQLAQLQAEITRLNTLPALK
ESPIIQQIHTIQALGQGNTDEAHQAINIGIELQMSWMNYVLLGKVYEMQGNNHLAADSYI
TAFNLRPGENTLHWISNAVFHTSINAVVPYLNNYTQSE