Protein Info for IAI46_19895 in Serratia liquefaciens MT49
Annotation: glutaredoxin-like protein NrdH
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 44% identical to NRDH_ECOLI: Glutaredoxin-like protein NrdH (nrdH) from Escherichia coli (strain K12)
KEGG orthology group: K06191, glutaredoxin-like protein NrdH (inferred from 94% identity to srs:SerAS12_3915)MetaCyc: 49% identical to mycoredoxin 2 (Corynebacterium glutamicum ATCC 13032)
Predicted SEED Role
"Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib" in subsystem Glutaredoxins or Glutathione: Redox cycle or Ribonucleotide reduction
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (78 amino acids)
>IAI46_19895 glutaredoxin-like protein NrdH (Serratia liquefaciens MT49) MSIIIYSKPDCVQCNATYRAFDKQGIGYQVIDLTQDQQALNHVKSLGYQQVPVIIAGEDH WSGFRPDKIGALAHALAS