Protein Info for IAI46_19640 in Serratia liquefaciens MT49

Annotation: outer membrane protein assembly factor BamE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF04355: SmpA_OmlA" amino acids 35 to 104 (70 residues), 96.8 bits, see alignment E=2.5e-32

Best Hits

Swiss-Prot: 87% identical to BAME_SALTY: Outer membrane protein assembly factor BamE (bamE) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K06186, small protein A (inferred from 99% identity to spe:Spro_3687)

Predicted SEED Role

"Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (112 amino acids)

>IAI46_19640 outer membrane protein assembly factor BamE (Serratia liquefaciens MT49)
MRCKTLTAAAVVLVMLTAGCSTFEKVVYRPDINQGNYLTSTDVAKIQKGMTQQQVAYTLG
TPMLQDPFGTQTWFYVFRQQPGHENVTQQTLTLTFNSAGVLTDIQNKPALTK