Protein Info for IAI46_19225 in Serratia liquefaciens MT49

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 241 to 264 (24 residues), see Phobius details amino acids 279 to 301 (23 residues), see Phobius details amino acids 313 to 333 (21 residues), see Phobius details amino acids 339 to 363 (25 residues), see Phobius details amino acids 380 to 398 (19 residues), see Phobius details amino acids 405 to 425 (21 residues), see Phobius details PF07690: MFS_1" amino acids 29 to 389 (361 residues), 196.6 bits, see alignment E=2.8e-62

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 98% identity to spe:Spro_3599)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (435 amino acids)

>IAI46_19225 MFS transporter (Serratia liquefaciens MT49)
MSVEINQRVADTGRRKFKSLRWWMLALFLLGVTVNYITRNSLGILAPELKTSLNMTTEQY
SWVVASFQLAYTVFQPICGWLIDVIGLKMGFLICASIWAVVCMLHAGAGSWLQLAILRFF
MGGAEAAATPANAKAISDWFPKKERPIAAGWAGVGFSIGAMLAPPIIVIAHVSFGWQGAF
LFSGALALIWVVLWWLFYHSPQQHPNLSQQELDLIREDNEPELPRLPFLKSLAILCRNKK
FYGIAIPAFLAEPAWAVFSFWVPLYLATERGMDLKHIAMFAWLPFLAADIGSVASGYLTT
LYRKWFGCSRVNSVVASSVTGAFMMVSLAFVAITKDPYVAIALISIGGFGHQVISCMLSA
LVVESFDKNQMATVNGMRGSSAWIASFLFTLLIGAVSDTVGFNPLFIAMGFFDLIGALFL
IALIAERGGKKTLNS