Protein Info for IAI46_19180 in Serratia liquefaciens MT49

Annotation: helix-turn-helix transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 120 PF01638: HxlR" amino acids 21 to 107 (87 residues), 75.2 bits, see alignment E=1.5e-25

Best Hits

Swiss-Prot: 34% identical to YTFH_ECOLI: Uncharacterized HTH-type transcriptional regulator YtfH (ytfH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 88% identity to srs:SerAS12_3790)

Predicted SEED Role

"Transcriptional regulator, HxlR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (120 amino acids)

>IAI46_19180 helix-turn-helix transcriptional regulator (Serratia liquefaciens MT49)
METNETVYRADCPSRIILDQIADKWSMMVLEVLREPRRFNAIKRRLDGVTQRVLTQTLRK
LERNGMVNRKVLDGRVLGVEYSLTPLGQSLQGPFSILFEWTMGNMEAIQDCRRRYDEQNQ