Protein Info for IAI46_19015 in Serratia liquefaciens MT49

Annotation: tRNA 5-hydroxyuridine modification protein YegQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01136: Peptidase_U32
  • amino acids 78 to 342 (265 residues), 289.1 bits, E=2.1e-90
• PF16325: Peptidase_U32_C
  • amino acids 359 to 440 (82 residues), 81.3 bits, E=4.6e-27

Best Hits

Swiss-Prot: 83% identical to YEGQ_ECOLI: Uncharacterized protease YegQ (yegQ) from Escherichia coli (strain K12)

KEGG orthology group: K08303, putative protease [EC: 3.4.-.-] (inferred from 98% identity to spe:Spro_3561)

Predicted SEED Role

"Putative protease"

KEGG Metabolic Maps

• Biotin metabolism
• Lysine degradation
• Peptidoglycan biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Protein Sequence (450 amino acids)

>IAI46_19015 tRNA 5-hydroxyuridine modification protein YegQ (Serratia liquefaciens MT49)
MFTPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLAQGINEAHALGK
RFYVVVNIAPHNAKLKTFLRDLKPVIDMGPDALIMSDPGLIMMVREAFPQMDIHLSVQAN
AVNWATVKFWQQMGLTRVILSRELSLEEIAEIRTQVPEMELEIFVHGALCMAYSGRCLLS
GYINKRDPNQGTCTNACRWQYKAEEGKEDETGNIVHMHEPIPVQTVEPTLGIGAPTDKVF
MLSEAQKPGEYMSAFEDEHGTYIMNSKDLRAIQHVERLTQLGVHSLKIEGRTKSFYYCAR
TAQVYRRAIDDAVAGKPFDPTLLTTLEGLAHRGYTEGFLRRHVHEAQQNYDYGSSLSERQ
QFVGEFTGVRRDGWAEVDVKNKFLLGDSVEMMTPGGNVLFTLESMQNKKGEAIDVAPGNG
HIVYLPIPQDIDLNYALLIRNLPDTNTPAA