Protein Info for IAI46_18650 in Serratia liquefaciens MT49

Annotation: cytochrome c-type protein NapC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 transmembrane" amino acids 29 to 49 (21 residues), see Phobius details TIGR02161: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family" amino acids 17 to 199 (183 residues), 343 bits, see alignment E=2.2e-107 PF03264: Cytochrom_NNT" amino acids 27 to 198 (172 residues), 269.8 bits, see alignment E=2.3e-84

Best Hits

Swiss-Prot: 79% identical to NAPC_ECOL6: Cytochrome c-type protein NapC (napC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02569, cytochrome c-type protein NapC (inferred from 98% identity to spe:Spro_3484)

MetaCyc: 56% identical to NapC (Aliivibrio fischeri)
RXN-15816 [EC: 7.1.1.8]

Predicted SEED Role

"Cytochrome c-type protein NapC" in subsystem Nitrate and nitrite ammonification or trimethylamine N-oxide (TMAO) reductase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.1.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>IAI46_18650 cytochrome c-type protein NapC (Serratia liquefaciens MT49)
MSERKHTTTEKKPGLLLRLWRWWRRPSRLALGTLLLLGFGAGIIFWGGFNTGMEAANTEQ
FCIGCHEMRENVYEEYMGTVHYNNRSGVRATCPDCHVPHEWAPKMLRKIKASKELYAKAF
GLIDTPQKFDQHRLAMASNEWARMKANDSQECRNCHNFEYMDFTAQKTVAAKMHDKAVTE
GKTCIDCHKGIAHKLPDMRDVPNGF