Protein Info for IAI46_18610 in Serratia liquefaciens MT49
Annotation: chitinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 93% identical to CHIB_SERMA: Chitinase B (chiB) from Serratia marcescens
KEGG orthology group: K01183, chitinase [EC: 3.2.1.14] (inferred from 97% identity to spe:Spro_3476)MetaCyc: 93% identical to chitinase B (Serratia marcescens)
RXN-12309 [EC: 3.2.1.200]; 3.2.1.200 [EC: 3.2.1.200]
Predicted SEED Role
"Chitinase (EC 3.2.1.14)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.14)
MetaCyc Pathways
- chitin degradation III (Serratia) (7/7 steps found)
- chitin degradation II (Vibrio) (4/6 steps found)
- chitin degradation I (archaea) (3/7 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.14
Use Curated BLAST to search for 3.2.1.14 or 3.2.1.200
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (499 amino acids)
>IAI46_18610 chitinase (Serratia liquefaciens MT49) MSERKAVIGYYFIPTNQINHYTESDTSIVPFPVSNITPAKARQLTHINFSFLDINSNLEC AWDPETNDAKARDVVSRLTALKAHNPNLRIMFSIGGWYYSNDLGVSHANYVNAVKTPAAR TKFAQSCVRIMKDYGFDGVDIDWEYPQSSEVDGFVAALQEIRTLLNQQTQADGRQALPYQ LTIAGAGGAFFLSRYYSKLPQIVASLDYINLMTYDLAGPWEKITNHQAGLFGDSAGPTFY NALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMLEGVPSSKIVMGVPFYGRAFKGVS ATNGGQYSSHSTPGEDPFPGTDYWLVGCEECVRDKDPRIASYRQLEQMLLGNYGYQRLWN DKTKTPYLYHAANGLFVTYDDAESFKYKAKYIKQQQLGGVMFWHLGQDNRNGDLLASLDR YFNAPDYDDSQLDMGTGLRYTGVGPGNLPIMSAPAYVAGTTYNQGALVSYQGYVWQAKWG YITAVPGSDTAWLKVGRVA