Protein Info for IAI46_18515 in Serratia liquefaciens MT49

Annotation: Dyp-type peroxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04261: Dyp_perox_N
  • amino acids 5 to 131 (127 residues), 114.8 bits, E=3.5e-37
• TIGR01413: Dyp-type peroxidase family
  • amino acids 5 to 295 (291 residues), 293.5 bits, E=1.1e-91
• PF20628: Dyp_perox_C
  • amino acids 134 to 293 (160 residues), 204.2 bits, E=1.2e-64

Best Hits

Swiss-Prot: 66% identical to YFEX_ECO57: Dye-decolorizing peroxidase YfeX (yfeX) from Escherichia coli O157:H7

KEGG orthology group: K07223, putative iron-dependent peroxidase (inferred from 99% identity to spe:Spro_3458)

MetaCyc: 66% identical to porphyrinogen peroxidase (Escherichia coli K-12 substr. MG1655)
PROTOHEMEFERROCHELAT-RXN [EC: 4.98.1.1]; RXN-11813 [EC: 4.98.1.1, 1.11.1.19]; RXN0-7325 [EC: 4.98.1.1, 1.11.1.19]

Predicted SEED Role

"Predicted dye-decolorizing peroxidase (DyP), encapsulated subgroup"

MetaCyc Pathways

• superpathway of heme b biosynthesis from glutamate (10/10 steps found)
• superpathway of heme b biosynthesis from glycine (8/8 steps found)
• superpathway of heme b biosynthesis from uroporphyrinogen-III (6/6 steps found)
• heme b biosynthesis I (aerobic) (4/4 steps found)
• heme b biosynthesis II (oxygen-independent) (4/4 steps found)
• heme b biosynthesis V (aerobic) (4/4 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.11.1.19 or 4.98.1.1

Protein Sequence (299 amino acids)

>IAI46_18515 Dyp-type peroxidase (Serratia liquefaciens MT49)
MTQVQSGILLEHCRFAIFMEATVQGEFADLRQGCKQFCQTLTELQQQFPDAHLGAVIAFG
YDVWHDLSSGQGAKELKPFTPLGKGLAPATQRDLLIHIQSLRHDVNFTLAQAALAAFGNA
IKIEEETHGFRWVEERDLSGFIDGTENPQGDKRPEVAVIAEGEEDAGGSYVLVQRYEHNL
RQWQRFTTEQQEQIIGRTKHDSEELPPEQRPDTSHVSRVDLKEDGKGLKILRQSLPYGTA
SGKHGLYFIAYCARLHNIEKQLLSMFGDLDGKRDAMLRFSRAVTGSYYFAPSLTRLLSL