Protein Info for IAI46_18370 in Serratia liquefaciens MT49

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 759 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF07715: Plug" amino acids 64 to 178 (115 residues), 100.3 bits, see alignment E=9.1e-33 TIGR01783: TonB-dependent siderophore receptor" amino acids 65 to 759 (695 residues), 390.9 bits, see alignment E=6.5e-121 PF00593: TonB_dep_Rec" amino acids 285 to 712 (428 residues), 187.1 bits, see alignment E=1.1e-58

Best Hits

Swiss-Prot: 72% identical to FEPA_ECOLI: Ferrienterobactin receptor (fepA) from Escherichia coli (strain K12)

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 95% identity to spe:Spro_3430)

MetaCyc: 72% identical to ferric enterobactin outer membrane transporter (Escherichia coli K-12 substr. MG1655)
RXN0-1682

Predicted SEED Role

"TonB-dependent receptor; Outer membrane receptor for ferric enterobactin and colicins B, D"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (759 amino acids)

>IAI46_18370 TonB-dependent siderophore receptor (Serratia liquefaciens MT49)
MNSKLSRYSLATLIGLGLGASAFAHAAQQTDTTPETDKVAKSKKEAAEDTIVVTAAKQNL
QAPGVSTITADEIKKRPPARDISELIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTL
ILIDGKPASSRNSVRQGWRGERDTRGDTAWVPPEMIERIEVLRGPAAARYGNGAAGGVVN
IITKKNTKELHGSLNTYFNVPEHKQEGSTKRTDFSLSGPLTDQLSFRLFGGYSKTQADAW
DINESHKSERVGAYASSIPSGREGVVDKNIDALLHWDFAHLQSLEFEYSYGRQGNLYAGD
TQNTNTNALVQSNYGKETNRIYRETFGLNHRGAWDNGVSTNNYVQFERTRNTRLNEGLAG
GTEGIFDAKNEGFGTTKLDDFLAHSEVSVPFELGVTQTATLGTEWNQQRMKDGSSTSQTM
MGGTIPGQGSGTRSPYASAHIFSLFAEDNMELTDSTMLTPGLRYDLHSEAGNNWSPSLNL
SQELGDNFTLKMGIARAYKAPNLYQTNQNYLLYSKGQGCSSSDVKNGCYLLGNDDLKAET
SVNKEVGLEFHNEGWLAGVTYFRNDYHNKIEAGNSRIGTSSTGTAVYQWENVPKAVVQGL
EGTLNVPVSETVSWSNNATYMIENKNKSTGDYLSVIPKFTINSTLSWQATQDLSMQSTLT
WYGRQKPKKYNYQGKPVSGTETKEVSPYAVVGASATYDVTKNISLTAGIDNLFDKRQFRE
GNSQNVGDPTTGAINIAGAGAATYNEPGRTYYMSVNTHF