Protein Info for IAI46_18210 in Serratia liquefaciens MT49

Annotation: OFA family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 transmembrane" amino acids 10 to 29 (20 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 216 to 237 (22 residues), see Phobius details amino acids 249 to 270 (22 residues), see Phobius details amino acids 282 to 300 (19 residues), see Phobius details amino acids 306 to 330 (25 residues), see Phobius details amino acids 342 to 360 (19 residues), see Phobius details amino acids 366 to 387 (22 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 302 (283 residues), 89 bits, see alignment E=1.5e-29 amino acids 219 to 401 (183 residues), 65.7 bits, see alignment E=1.8e-22

Best Hits

Swiss-Prot: 45% identical to YHJX_ECOLI: Uncharacterized MFS-type transporter YhjX (yhjX) from Escherichia coli (strain K12)

KEGG orthology group: K08177, MFS transporter, OFA family, oxalate/formate antiporter (inferred from 96% identity to spe:Spro_3406)

Predicted SEED Role

"Oxalate/formate antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>IAI46_18210 OFA family MFS transporter (Serratia liquefaciens MT49)
MNTKPVNRSLIVLGTIICQMGLGTIYTWSLFNQPLVDKFHWGLGDVATTFSITSFFLAFA
TLFAGKLQERFGIRNLTLFSGILVGLGLIASAYVSSLDMIYLLAGVVVGFAVGIAYISTL
SNLIKWFPANKGLISGISVGAFGSGSLLFKYVNAALIADVGVSSAFFYWGAIVMALIVLG
SLLLKEPVLASKSAQQSAGNLGNDFSVRQMLATKEAYLLFMIFFAACMSGLYLIGIVKDM
GVQLAGMDLATAANTVSAVAIFNTAGRIILGTLSDKVGRMRVISFTMLVTVLAIVALSFL
TLNHTLFFICVGAVAFCFGGNITVFPAIVGDFFGLKNHSKNYGIIYQGFGLGALAGSFVA
KYFGGFHATFMVIGVLSIASLIITLFIKAPKAVAQEEETFEPAHLAKA