Protein Info for IAI46_18090 in Serratia liquefaciens MT49
Annotation: cytochrome c maturation protein CcmE
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to CCME_SERP5: Cytochrome c-type biogenesis protein CcmE (ccmE) from Serratia proteamaculans (strain 568)
KEGG orthology group: K02197, cytochrome c-type biogenesis protein CcmE (inferred from 100% identity to spe:Spro_3387)MetaCyc: 68% identical to periplasmic heme chaperone (Escherichia coli K-12 substr. MG1655)
RXN-21407
Predicted SEED Role
"Cytochrome c-type biogenesis protein CcmE, heme chaperone" in subsystem Biogenesis of c-type cytochromes
MetaCyc Pathways
- cytochrome c biogenesis (system I type) (9/11 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (164 amino acids)
>IAI46_18090 cytochrome c maturation protein CcmE (Serratia liquefaciens MT49) MNPRRKSRLYLAIVVLIGVALTATLMLYALRSNIDLFYTPSEILQGKGENHEKPEVGQRL RIGGMVMPGSVKRDQKTLQVSFKVYDARGAIDVTYTGILPDLFREGQGVVAQGVLGEGNV VNAREVLAKHDEKYTPPEVADAMKENHKGPASAYATPQNEGAKS