Protein Info for IAI46_17815 in Serratia liquefaciens MT49

Annotation: colicin V production protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 31 to 52 (22 residues), see Phobius details amino acids 64 to 87 (24 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details PF02674: Colicin_V" amino acids 4 to 142 (139 residues), 134.8 bits, see alignment E=1.1e-43

Best Hits

Swiss-Prot: 86% identical to CVPA_ECOLI: Colicin V production protein (cvpA) from Escherichia coli (strain K12)

KEGG orthology group: K03558, membrane protein required for colicin V production (inferred from 99% identity to srs:SerAS12_3528)

Predicted SEED Role

"Colicin V production protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (166 amino acids)

>IAI46_17815 colicin V production protein (Serratia liquefaciens MT49)
MVWIDYVIIAVIGFSALVSLIRGFVREALSLVTWGCAFFVASHFYSYLAVYFTRFEDELV
RNGIAIAILFIATLIVGAIVNYVISSLVEKTGLSGTDRVLGVCFGALRGVLIVSAILFFL
DTFTGFSQSADWKQSQLIPQFSYIIRWFFDYLQSTSSFLPTHLPGR