Protein Info for IAI46_17780 in Serratia liquefaciens MT49

Annotation: TIGR01777 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 248 to 268 (21 residues), see Phobius details PF01370: Epimerase" amino acids 3 to 215 (213 residues), 73.7 bits, see alignment E=1.6e-24 TIGR01777: TIGR01777 family protein" amino acids 3 to 293 (291 residues), 369.9 bits, see alignment E=5.7e-115 PF08338: DUF1731" amino acids 250 to 296 (47 residues), 70.3 bits, see alignment 9.2e-24

Best Hits

Swiss-Prot: 70% identical to YFCH_ECOLI: Epimerase family protein YfcH (yfcH) from Escherichia coli (strain K12)

KEGG orthology group: K07071, (no description) (inferred from 94% identity to spe:Spro_3322)

Predicted SEED Role

"Cell division inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>IAI46_17780 TIGR01777 family protein (Serratia liquefaciens MT49)
MRILITGATGLIGSSLTRRLLGLSHQVTVLSRNVPRARERFGEQVSYWSTLQDQPSLDGF
DAVINLAGEPIADKRWSKAQKERLCHSRWDLTEQLVKLINAGSNPPSVLISGSATGYYGD
QGQAVVTEDEAPHDEFTHQLCQRWESLALQAQSDATRVCLLRTGVVLAAKGGALAKMLPP
FRFGLGGPIGSGRQYLPWIHLDDMVNGIIYLLDHQTLQGPFNMVAPYPVHNEQFAAQLAN
VLDRPAFLRVPAFAMHLLMGEAAVLVLGGQRAVPKRLEEAGFSFRFLELEQALDDVINQR
DPVR