Protein Info for IAI46_17525 in Serratia liquefaciens MT49

Annotation: tyrosine transporter TyrP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details amino acids 28 to 28 (1 residues), see Phobius details transmembrane" amino acids 20 to 27 (8 residues), see Phobius details amino acids 36 to 58 (23 residues), see Phobius details amino acids 79 to 100 (22 residues), see Phobius details amino acids 120 to 138 (19 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 182 to 204 (23 residues), see Phobius details amino acids 216 to 235 (20 residues), see Phobius details amino acids 276 to 299 (24 residues), see Phobius details amino acids 311 to 329 (19 residues), see Phobius details amino acids 335 to 357 (23 residues), see Phobius details amino acids 370 to 398 (29 residues), see Phobius details PF03222: Trp_Tyr_perm" amino acids 1 to 389 (389 residues), 460.5 bits, see alignment E=5.6e-142 PF01490: Aa_trans" amino acids 6 to 208 (203 residues), 43.2 bits, see alignment E=2.2e-15 TIGR00837: aromatic amino acid transport protein" amino acids 7 to 383 (377 residues), 457.2 bits, see alignment E=2.8e-141

Best Hits

Swiss-Prot: 80% identical to TYRP_ECOLI: Tyrosine-specific transport protein (tyrP) from Escherichia coli (strain K12)

KEGG orthology group: K03834, tyrosine-specific transport protein (inferred from 98% identity to spe:Spro_3276)

Predicted SEED Role

"Tyrosine-specific transport protein" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>IAI46_17525 tyrosine transporter TyrP (Serratia liquefaciens MT49)
MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFGVTLALLVGLWLLMCYTALLLVEVYQH
EQADTGLGTLAKRYLGGGGQWLTSFSMMFLMYALTAAYISGAGELLAASISQWTSQDFPT
TLGVLLFTLVAGGVVCIGTHSVDLFNRILFSAKVVFLIVMLGLMLPNIHQTNLMTLPLEQ
GLALSAIPVIFTSFGFHGSVPSIVNYMGGNIRKLRWVFIIGSAIPLIAYIFWQLATLGSI
SSTTFVGILAQQAGLNGLLQAVRDVVASPHVELAVHLFADLALATSFLGVALGLFDFLAD
LFKRQDNVRGRLQTGAITFLPPLAFALFYPRGFVLALGFAAIALAVLALLLPSMLVWKTR
QQHQAKYRVWGGTPALAVVFVCGVTVIAIQVGIASGILPAVG