Protein Info for IAI46_16975 in Serratia liquefaciens MT49

Annotation: anion permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 33 to 50 (18 residues), see Phobius details amino acids 57 to 75 (19 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 138 to 156 (19 residues), see Phobius details amino acids 193 to 216 (24 residues), see Phobius details amino acids 235 to 259 (25 residues), see Phobius details amino acids 288 to 304 (17 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 341 to 365 (25 residues), see Phobius details amino acids 380 to 412 (33 residues), see Phobius details amino acids 424 to 450 (27 residues), see Phobius details amino acids 461 to 483 (23 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 6 to 485 (480 residues), 593.6 bits, see alignment E=3.5e-182 TIGR00785: transporter, divalent anion:Na+ symporter (DASS) family" amino acids 25 to 479 (455 residues), 528.5 bits, see alignment E=6.1e-163 PF03600: CitMHS" amino acids 46 to 386 (341 residues), 64.2 bits, see alignment E=1.2e-21 amino acids 300 to 482 (183 residues), 39.7 bits, see alignment E=3.4e-14

Best Hits

Swiss-Prot: 81% identical to CITT_ECO57: Citrate/succinate antiporter (citT) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 96% identity to srr:SerAS9_3289)

MetaCyc: 81% identical to citrate:succinate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-201

Predicted SEED Role

"Citrate Succinate antiporter (TC 2.A.47.3.2)" (TC 2.A.47.3.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>IAI46_16975 anion permease (Serratia liquefaciens MT49)
MSETKEKIWKALAPLLVLAILLWIPTPDGMPPQAWRYFAIFVAMIVGMILEPIPATAISF
IAVTLSVLSANWVLFGAQELAEPGFKAGKEALKWGLAGFSSTTVWLVFGAFIFALGYEAT
GLGRRIALFLVKFMGKRTLTLGYAVVIIDILLAPFTPSNTARTGGTVFPVVKNLPPLFDS
FPNDPSSRRIGGYLMWMMVVGTSISSSMFVTGAAPNVLGIEFVSKIAGVHISWMQWFLAF
LPVGLLLLVIAPLISYYLYKPGVTHSSEVASWANSALGEMGKLTRKEYTLIGLVLLSLCL
WVFGGKILDATTVCLLAVSLMLALHVVSWKDITKYSSAWNTLVNLATLVVMANGLTRSGF
IDWFALTMSTHLDGFSPDMTVVALVLVFYFAHYLFASLSAHTATLLPVILAVGKGLPGVP
MEQLSMLLVLSIGIMGVLTPYATGPGVIIYGCGYVKSKDYWRMGGILGVVYIAALLLIGW
PIMRLWM