Protein Info for IAI46_16530 in Serratia liquefaciens MT49

Annotation: NAD-dependent epimerase/dehydratase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF01370: Epimerase" amino acids 5 to 198 (194 residues), 95.7 bits, see alignment E=1.1e-30 PF05368: NmrA" amino acids 5 to 115 (111 residues), 42.2 bits, see alignment E=2.4e-14 PF01073: 3Beta_HSD" amino acids 6 to 190 (185 residues), 48.9 bits, see alignment E=1.7e-16 PF16363: GDP_Man_Dehyd" amino acids 7 to 111 (105 residues), 43.7 bits, see alignment E=9.4e-15 PF13460: NAD_binding_10" amino acids 9 to 134 (126 residues), 63.8 bits, see alignment E=6.8e-21 PF07993: NAD_binding_4" amino acids 55 to 115 (61 residues), 22.7 bits, see alignment E=1.7e-08

Best Hits

KEGG orthology group: None (inferred from 74% identity to ebi:EbC_37160)

Predicted SEED Role

"FIG010773: NAD-dependent epimerase/dehydratase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>IAI46_16530 NAD-dependent epimerase/dehydratase family protein (Serratia liquefaciens MT49)
MTGTVAVTGVTGFIGRHIVQNLLSRGFTVRALTRRAGQIAPSNLTWIQGALEDQDSLIEL
VRGAEFVVHCAGQVRGGTEETFTRCNVSGSQHLMQAARQSGSCKRFLFISSLAARHPELS
WYANSKHVAEQRLTAMAADISLGIFRPTAVYGPGDKELKPIFSWLLRGVLPRLGAAEAKL
TFLHVSDLAEAVSQWLLAPGPQTQTYELCDGVAGGYSWQRLREIGTTVRNGPVRLVGIPL
PLLKILADGSMLLSRLTNKEPMLTHNKIRELTYPDWSANNRSLSEDTHWVPKISLKRALR
EGLF