Protein Info for IAI46_16330 in Serratia liquefaciens MT49

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 299 to 320 (22 residues), see Phobius details PF02743: dCache_1" amino acids 52 to 241 (190 residues), 56.7 bits, see alignment E=2.5e-19 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 347 to 514 (168 residues), 165.9 bits, see alignment E=3.2e-53 PF00990: GGDEF" amino acids 351 to 512 (162 residues), 159.4 bits, see alignment E=6.7e-51

Best Hits

KEGG orthology group: None (inferred from 92% identity to spe:Spro_3068)

Predicted SEED Role

"Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>IAI46_16330 diguanylate cyclase (Serratia liquefaciens MT49)
MTQQQPQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNGWQIWNAHQRDLQSAENESAN
LARSLAQHADDTFMQTDTTLSDLTERIQTDGLGQPQQLRLQKVMQTQVGNLPQLHGLFVY
DAQGNWIVTSSGRFIQNANNADREYFKFHLSHNSNAIFIGKVVRSRSTGDLIIPVSRRIN
NPDGSFNGVVLATLYVDYFRQFYDTFALNSDASLNLLLADGTILYRRPYSIAAIGKNISE
GVLFREILPHSEFGNATITSRYDKVERIYGYSRVNRYPLVIAAGLSKEDALSDWRNDTGV
FALGGATLLIILLAMGLVLMRQINHSVRTEAELMRTRDQLTTINRTLEELALLDGLTGLA
NRRQFDIAMKNELMRASRNYRSVALLMLDIDCFKQYNDIYGHVAGDQCLQQIGQTLKGLA
CRSNDIMARYGGEEMAIILPDTDTQGALIFAERVIESVRELKIPHTGNPHGIVTISIGIF
AKVPHMYNDTPIGFINQADSALYQAKAQGKNRIYPA